COLUMBIA, Mo. — Paul Thompson threw two touchdown passes and ran for another score as No. 19 Oklahoma turned five Missouri mistakes into points in a 26-10 victory Saturday.
Two interceptions, a fumble, a blocked punt and a roughing the kicker penalty set up every score for Oklahoma (6-2, 3-1 Big 12), which beat No. 23 Missouri for the 15th time in 16 tries.
The Tigers (7-2, 3-2) lost at home for the first time in nine games. After a 6-0 start, Missouri has lost two of three.
Thompson was 11-for-19 for 127 yards, passed for two touchdowns and ran for another. Allen Patrick, in his second game as a starting for the injured Adrian Peterson, carried 36 times for 162 yards.
Missouri came in averaging 33.1 points, but struggled against the Sooners' 11th-ranked defense. Chase Daniel was 23-for-44 for 284 yards and three interceptions. He also ran 20 times for 75 yards and a score. Other than Daniel, Missouri gained 1 yard rushing on seven carries.
Things started promising for Missouri.
Leading 3-0, the Tigers missed a chance for a sure 66-yard touchdown when tight end Chase Coffman, uncovered down the right sideline, let a pass slip off his fingertips.
On the next play, Daniel's pass was tipped and linebacker Zach Latimer intercepted, giving Oklahoma the ball at the Missouri 33. That set up Thompson's 3-yard TD run on an option play to make it 7-0.
Oklahoma got the ball back when Tony Temple fumbled and Lendy Holmes recovered at the Oklahoma 42. The drive ended with Thompson's 18-yard scoring pass to Joe Jon Finley on the first play of the second quarter.
After Daniel's fumble resulted in a 21-yard loss, the Tigers were forced to punt from the 12. Oklahoma's Jason Carter blocked Adam Crossett's kick and Crossett recovered in the end zone for a safety.
Missouri took advantage of an Oklahoma turnover to cut the margin to 16-10 early in the third quarter. Patrick fumbled and Missouri recovered at its own 34. Daniel was 4-for-4 passing on the drive and ran the other four plays for 30 yards, including a 13-yard score on a quarterback draw.
Oklahoma was forced to punt on its next possession and the Tigers would have had the ball at midfield. But Missouri's William Moore was called for roughing the kicker. Given new life at their 35, the Sooners drove to the Missouri 15, where Thompson connected with Quentin Chaney for a touchdown.
The Tigers reached the Oklahoma 1 on their next drive. But on fourth-and-goal, Daniel's fade pass to Coffman was thrown too high.